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Malaria Quiz 12 Basic Questions

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順天堂大学医学部総合診療科学講座/マヒドン大学熱帯医学部・医学部

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Malaria Quiz 12 Basic Questions

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マラリアクイズの概要と目的

#1.

Malaria Quiz 12 Basic Questions Hirotake Mori h.mori.oa@juntendo.ac.jp Department of General Medicine, Faculty of Medicine, Juntendo University Faculty of Tropical Medicine, Mahidol University Unauthorized reproduction prohibited Microscopic identification of Malaria https://slide.antaa.jp/article/view/4114212c79ad4f66 マヒドン大学熱帯医学短期研修 http://mahidoltropicalmedicine.com/ Faculty of Tropical Medicine, Mahidol University https://www.tm.mahidol.ac.th/eng/index-eng.php

#2.

Introduction Malarial parasite microscopy characteristics will be used in a quiz format to explain. Please study using slideshow. Images published in Mahidol University Faculty of Tropical Medicine’s Atlas, and those seen in real life will be used. In clinical practice, there are many cases in which the images are not as easy to interpret as the ones in textbooks. Points used in the diagnosis of malaria are summarised in “malaria diagnosis points”. “Basic” will include easy to understand stereotypical/textbook cases. “Advanced” will include atypical examples at random.

マラリアの種類と特徴の記述

#3.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology (Faculty of Tropical Medicine, Mahidol University)

#4.

Malaria Quiz P. falciparum   Ring form stage (early trophozoite). A characteristic of the ring form of P. falciparum is a thin cytoplasm. Double infection, double chromatin is also observed. This is a typical finding in P. falciparum.

#5.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology (Faculty of Tropical Medicine, Mahidol University)

P. falciparumの成長段階と特徴

#6.

Malaria Quiz P. falciparum   Growing trophozoite This is the growing trophozoite stage of P. falciparum, a stage not commonly observed. Infected erythrocytes are not enlarged. Although few in number, Maurer's dots can also be seen.

#7.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#8.

Malaria Quiz P. falciparum  Schizont stage This is the schizont stage of P. falciparum.A large number of merozoites can be seen interiorly. Although difficult to count precisely, there appears to be around 20 merozoites. The brown colour in the center is malaria pigment.  

P. vivaxの成長段階と特徴

#9.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#10.

Malaria Quiz P. vivax   Growing trophozoite stage Given a large infected erythrocyte and the presence of Schuffner’s dots, P. vivax is diagnosed. Two parasites are observed so double infection is diagnosed.  A growing trophozite is concluded as the parasite cytoplasm is not enlarged.  

#11.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

P. vivaxの成熟段階と特徴

#12.

Malaria Quiz P. vivax  Late trophozoite stage P. vivax is diagnosed given the presence of Schuffner’s dots and a large infected erythrocyte. This parasite has a large cytoplasm and small vacuole so a late trophozoite is determined. Early trophozoite (ring form). The parasite cytoplasm is thin and the vacuole large giving a ring-like appearance. Growing trophozoite. The cytoplasm becomes thicker and the vacuole decreases in size. Late trophozoite. The parasite cytoplasm occupies a large portion of the erythrocyte and the vacuole becomes even smaller.

#13.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#14.

Malaria Quiz P. vivax   Schizont stage (mature schizont). P. vivax is diagnosed given the presence of Schuffner’s dots and a large infected erythrocyte. 16 merozoites can be seen. The number of merozoites is also consistent with P. vivax.

P. ovaleの成長段階と特徴

#15.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#16.

Malaria Quiz P. vivax   Gametocyte (macrogametocyte) P. vivax is diagnosed given the presence of Schuffner’s dots and a large infected erythrocyte.  Chromatin can be seen at the edge of the nucleus; a macrogametocyte is diagnosed.

#17.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

P. ovaleの成熟段階と特徴

#18.

Malaria Quiz P. ovale   Growing trophozoite The infected erythrocytes are large and distorted (fimbriated). Schuffner’s dots are also present so P. ovale is diagnosed. This is a stereotypical finding in P. ovale. 

#19.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#20.

Malaria Quiz P. ovale Schizont stage The infected erythrocyte is large and distorted (fimbriated). Schuffner’s dots are also present so P. ovale is diagnosed. 8 merozoites can be seen interiorly. Schizont stage is diagnosed.  

P. malariaeの成長段階と特徴

#21.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#22.

Malaria Quiz P. ovale Gametocyte (microgametocyte) The infected erythrocyte is large and distorted (fimbriated). Schuffner’s dots are also present so P. ovale is diagnosed.  A microgametocyte was diagnosed as chromatin is not observed.  

#23.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

P. malariaeの成熟段階と特徴

#24.

Malaria Quiz P. malariae   Growing trophozoite (band form). The infected erythrocyte is not enlarged and there are no dots. On top of this, the characteristic band-form finding is present allowing us to diagnose P. malariae.  

#25.

Malaria Quiz Please write the type (species) of malaria, its characteristics, and the stage of infection. Extract from Atlas of Medical Parasitology

#26.

Malaria Quiz P. malariae   Late trophozoite The infected erythrocyte is not enlarged and there are no dots. The diagnosis is P. malariae.  

マラリアクイズのまとめと終了

#27.

Good job We’ll end the basic malaria quiz here. Did you get the picture?

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